mds 0.3.0

Implemented Updates

General - Overall improvement of documentation & detailed descriptions of functions - Input parameter covariates specified in deviceevent() must be either factor or numeric, no longer character. - Input parameter match_levels specified in time_series() must be factor, no longer character. - Add to output of define_analyses() a function for adding dates in the units specified by date_level and date_level_n - Deprecated use_hierarchy parameter in time_series() - Explicit carry-forward of define_analysis id

Covariate Handling - Explicit handling of covariate level analysis in deviceevent(), define_analyses(), and time_series() - Added analysis data frame to time_series() output when covariate analysis is requested - Covariates can now be EITHER factor OR numeric types when defined in deviceevent(). Previously only characters (inferred as factors) werea allowed. - Covariate analysis definitions include as a whole (marginal effect) or as a subset by a factor covariate level - Covariate analysis is exempt if there is zero variation in the data of the covariate - Restructured exposure() to handle factors only in match_levels.

Implantable Devices / Time In-Vivo Handling - Explicit handling of time in-vivo in deviceevent(), define_analyses(), and time_series() - Added analysis data frame to time_series() output when time in-vivo analysis is requested - CHANGED PARAMETER deviceevent(implant_days) to deviceevent(time_invivo) and make all downstream changes.

To-Do List - Feature allowing total events (concept of reporting fraction) as an exposure data frame - Facility for handling multiple events on the same actual occurrence (such as stroke and bleeding during the same operation) - Explicit implementation of the Unique Device Identifier (UDI) - Implementation of IMDRF coding for product malfunctions, patient adverse events, and analysis findings

mds 0.2.1

Implemented Updates

# mds 0.2.0

Implemented Updates

Bugfixes

# mds 0.1.0